Claude

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On Oct 20, 2026, Anthropic reported that an internal research model running inside Claude Science autonomously designed protein binders against scorpion neurotoxins: 318,484 designs filtered to 211 sent to the lab, 17 confirmed binders at two labs. This piece checks the numbers and the limits, takes apart the explore→filter→wet-lab-truth loop, and offers a framework for reading autonomous science-agent results.

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Haiku 5.5 lists at USD 0.10/0.50 per million tokens, but any prompt over 100K tokens bills the whole request at 5x, and the new tokenizer, on-by-default thinking, and cache rules all move the bill. Per-request formulas, three worked examples, the 12x-vs-GPT-6-Luna counter-case, and an acceptance checklist.

Featured · overlaps parent/sibling tag

Reading Anthropic’s guest post on Fable 5.1 inside Claude Science: planar N=4 SYM nine-loop hexagon amplitudes via an explicit science harness and minimal human intervention—harness × agent-loop, not a bigger-model story.

Featured · overlaps parent/sibling tag

Anthropic says Claude found ART (array-associated reverse transcriptases) under high-level direction. This post cross-checks the news post and technical report: search discovery vs unknown function, reproducibility limits, research-agent pipelines, and how builders should read the story.